Finding Your Way to Louisbourg Louisbourg is a 25-minute drive (23 miles) on Route 22 from Sydney, on the southeast coast of Cape Breton Island. Route 22 from Sydney becomes Main Street, Louisbourg, and our B&B is on the right-hand side just past the Post Office at the corner of Lower Warren and Main. Directions Nova Scotia road map (directions from Halifax to Louisbourg) Our location in Louisbourg Driving Times to Louisbourg (non-stop) Halifax - shortest (Routes 102, at Truro 104, at St. Peters 4, at Sydney 22) - 5 hours Halifax - via Marine Drive (Routes 107, at Musquodoboit Harbour 7, at Antigonish 104, at St. Peters, 4, at Sydney 22) - 6.5 hours Route 327 on Cape Breton Island, what appears to be a coastal route from St. Peters area to Louisbourg, is not recommended based on conditions and on a survey of previous guests. Yarmouth - 8 hours Pictou (PEI ferry) - 3.5 hours Amherst - 4.5 hours Cabot Trail (St. Anns) - 1 hour Canso Causeway (Port Hastings) - 2 hours Sydney Airport - 35 minutes North Sydney (Newfoundland ferry) - 40 minutes